Melanoma is a malignant skin tumor that threatens human life and health.Early detection is essential for effective treatment.However, the low contrast between melanoma lesions and normal skin and the irregularity in size and shape make skin lesions difficult to detect with the naked eye in the early stages, lunch bag making the task of skin lesion
Residual stress inevitably occurs at the weld in the process of manufacturing thick pressure hulls for manned submersibles, which affects the bearing capacity of the hull.In this study, an electron-beam-welded 32 mm-thick Ti-6Al-4V plate specimen is first tested, then the measured data of residual Dog stress distribution is applied to validate the
To effectively nurture the talents of elementary students with mathematical talent they need to be challenged with an advanced curriculum that is designed with their specific needs in mind.The purpose of this paper is to describe an effective model for developing such a curriculum and explore effective, research-based examples of curriculum and ins
We previously demonstrated endocytosis of KCa2.3 is caveolin-1-, dynamin II- and Rab5-dependent.KCa2.3 then enters Rab35/EPI64C- and RME-1-containing recycling endosomes and is returned to the plasma membrane (PM).Herein, we report on the mechanism by which KCa2.3 is inserted into the PM during recycling and following exit from the Golgi.We demonst